Connie Sanchez Selected Research

Vortioxetine

11/2020	Sub-chronic vortioxetine (but not escitalopram) normalizes brain rhythm alterations and memory deficits induced by serotonin depletion in rats.
1/2019	Effect of clinically relevant doses of vortioxetine and citalopram on serotonergic PET markers in the nonhuman primate brain.
1/2018	The multimodal antidepressant vortioxetine may facilitate pyramidal cell firing by inhibition of 5-HT3 receptor expressing interneurons: An in vitro study in rat hippocampus slices.
1/2018	Vortioxetine Treatment Reverses Subchronic PCP Treatment-Induced Cognitive Impairments: A Potential Role for Serotonin Receptor-Mediated Regulation of GABA Neurotransmission.
1/2017	In vivo and in vitro effects of vortioxetine on molecules associated with neuroplasticity.
1/2017	Acute dosing of vortioxetine strengthens event-related brain activity associated with engagement of attention and cognitive functioning in rats.
1/2017	Drugs with antidepressant properties affect tryptophan metabolites differently in rodent models with depression-like behavior.
9/2016	A single dose of vortioxetine, but not ketamine or fluoxetine, increases plasticity-related gene expression in the rat frontal cortex.
7/2016	Differential interaction with the serotonin system by S-ketamine, vortioxetine, and fluoxetine in a genetic rat model of depression.
1/2016	Task- and Treatment Length-Dependent Effects of Vortioxetine on Scopolamine-Induced Cognitive Dysfunction and Hippocampal Extracellular Acetylcholine in Rats.

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Connie Sanchez Research Topics

Disease

10	Cognitive Dysfunction 01/2020 - 04/2014
9	Major Depressive Disorder (Major Depressive Disorders) 12/2019 - 10/2014
4	Memory Disorders (Memory Loss) 11/2020 - 01/2014
3	Mood Disorders (Mood Disorder) 01/2020 - 02/2013
2	AIDS-Related Complex (ARC) 01/2017 - 01/2015
1	Pain (Aches) 01/2021
1	DiGeorge Syndrome (Syndrome, DiGeorge) 12/2020
1	Insulin Resistance 10/2019
1	Schizophrenia (Dementia Praecox) 10/2019
1	Weight Gain 10/2019
1	Neuroinflammatory Diseases 10/2018
1	Substance-Related Disorders (Drug Abuse) 01/2018
1	Neuroblastoma 01/2018
1	Inflammation (Inflammations) 01/2017
1	Tuberculosis (Tuberculoses) 05/2014
1	Lordosis 03/2004

Drug/Important Bio-Agent (IBA)

15	VortioxetineIBA 11/2020 - 01/2014
10	Antidepressive Agents (Antidepressants)IBA 01/2019 - 01/2014
7	Serotonin (5 Hydroxytryptamine)IBA 11/2020 - 03/2004
4	Glutamic Acid (Glutamate)FDA Link 01/2018 - 04/2014
3	Opioid Analgesics (Opioids)IBA 01/2020 - 01/2018
2	mu Opioid Receptors (mu Opioid Receptor)IBA 01/2021 - 12/2019
2	Escitalopram FDA Link 11/2020 - 01/2014
2	3-carboxamido-4-hydroxynaltrexoneIBA 12/2019 - 10/2019
2	gamma-Aminobutyric Acid (GABA)IBA 01/2018 - 01/2015
2	Proteins (Proteins, Gene)FDA Link 01/2017 - 01/2015
2	Fluoxetine (Prozac)FDA LinkGeneric 01/2017 - 07/2016
2	Norepinephrine (Noradrenaline)FDA LinkGeneric 04/2015 - 02/2013
1	ParvalbuminsIBA 12/2020
1	1,2- dihexadecyl- sn- glycero- 3- phosphocholineIBA 11/2020
1	Pharmaceutical PreparationsIBA 01/2020
1	Buprenorphine (Subutex)FDA LinkGeneric 12/2019
1	kappa Opioid Receptors (kappa Opioid Receptor)IBA 12/2019
1	Glucose (Dextrose)FDA LinkGeneric 10/2019
1	Olanzapine (Zyprexa)FDA Link 10/2019
1	Narcotic Antagonists (Opioid Antagonists)IBA 10/2019
1	Antipsychotic Agents (Antipsychotics)IBA 10/2019
1	Neurotransmitter Agents (Neurotransmitter)IBA 10/2018
1	Opiate AlkaloidsIBA 01/2018
1	Opioid Receptors (Opioid Receptor)IBA 01/2018
1	Serotonin ReceptorsIBA 01/2018
1	Tryptophan (L-Tryptophan)FDA Link 01/2017
1	EsketamineIBA 07/2016
1	Scopolamine (Hyoscine)FDA Link 01/2016
1	Acetylcholine (Acetylcholine Chloride)FDA Link 01/2016
1	Selective Serotonin Reuptake Inhibitors (Serotonin Reuptake Inhibitors)IBA 04/2015
1	AMPA Receptors (AMPA Receptor)IBA 01/2015
1	Serotonin 5-HT1 Receptor AgonistsIBA 01/2015
1	AcidsIBA 01/2015
1	Serotonin 5-HT1 Receptor AntagonistsIBA 01/2015
1	Hormones (Hormone)IBA 01/2015
1	NeurosteroidsIBA 01/2015
1	Aminobutyrates (Aminobutyric Acid)IBA 01/2015
1	5-HT1D Serotonin ReceptorIBA 01/2015
1	Isoniazid (Ftivazide)FDA LinkGeneric 05/2014
1	Vilazodone HydrochlorideIBA 04/2014
1	5-HT1A Serotonin ReceptorIBA 01/2014
1	5-HT3 Serotonin Receptors (5 HT3 Receptor)IBA 01/2014
1	Duloxetine Hydrochloride (Cymbalta)FDA Link 01/2014
1	Dopamine (Intropin)FDA LinkGeneric 02/2013

Therapy/Procedure

2	Therapeutics 12/2019 - 01/2019